Due out on the xbox 360 & playstation 3, the title is inspired by the 2009 Family Guy episode "Road to the Multiverse." In this episode, Stewie and Brian use a remote control to travel to parallel universes, including destinations inspired by Walt Disney, The Flintstones, and one where Christianity never existed.

Family Guy: Back to the Multiverse will be the first console game set in series creator Seth MacFarlane's cartoon universe since the 2K Games published Family Guy in 2006. That game was developed by High Voltage Software and shipped for the Xbox, PlayStation 2, and PSP. It featured the original voice cast of the TV series, including MacFarlane,Family Guy: Back to the Multiverse follows Family Guy Online, which is a free-to-play PC title currently in beta stage.